Senior Jacob Rosenthal (Biology) co-authors paper in GBE

About GBE

Congratulations to Jacob Rosenthal, who co-authored this article in Genome Biology and Evolution, an open access journal published by Oxford University on behalf of the Society for Molecular Biology and Evolution:

"Patterns of Population Variation in Two Paleopolyploid Eudicot Lineages Suggest That Dosage-Based Selection on Homeologs Is Long-Lived."

AUTHORS:  Hao, Yue; Washburn, Jacob D.; Rosenthal, Jacob; Nielsen, Brandon; Lyons, Eric; Edger, Patrick P.; Pires, J. Chris; Conant, Gavin C.

GENOME BIOLOGY AND EVOLUTION  Volume: 10  Issue: 3  Pages: 999-1011
DOI: 10.1093/gbe/evy061  Published: MAR 2018
 
Partial abstract: Genes that are inherently subject to strong selective constraints tend to be overretained in duplicate after polyploidy. They also continue to experience similar, but somewhat relaxed, constraints after that polyploidy event. We sought to assess for how long the influence of polyploidy is felt on these genes' selective pressures. We analyzed two nested polyploidy events in Brassicaceae: the At-a genome duplication that is the most recent polyploidy in the model plant Arabidopsis thaliana and a more recent hexaploidy shared by the genus Brassica and its relatives... Our results paint a picture of the long-lived effects of polyploidy on plant genomes, suggesting that even yesterday's polyploids still have distinct evolutionary trajectories.

Co-authors include researchers from North Carolina State University, Cornell University, Clarion University of Pennsylvania, Michigan State University, and University of Missouri.  As indexed in Web of Science.