Friday, October 21, 2016

Gravitational-Wave Universe... lecture by Chiara Mingarelli

Dr. Chiara Mingarelli, Max Planck Institute for Radio Astronomy and California Institute of Technology, will speak at Oberlin College this coming week:

"The Gravitational-Wave Universe Seen by Pulsar Timing Arrays"
Tuesday, October 25, 2016
Wright Lecture Hall (W201), Wright Physics Laboratory
Science Center

Related reading in the science library collection includes:
Many others are accessible in print and online through OBIS. Search "gravitational wave*" to find a good number of them!

Wednesday, October 19, 2016

Looking forward to hearing Robert Krulwich on November 5

Robert Krulwich '69, co-host of Radiolab, will be the featured speaker at the Friends of the Library annual dinner on Saturday, November 5.  It is sure to be both informative and entertaining!  The talk is open to the public - arrive shortly before 8pm in the Root Room, Carnegie Building, to grab an open seat.

An example of Krulwich's ability to explain a complex and vexing topic in terms that are clearly understood is the collaboration of NPR and Odd Todd animations to create the five episodes of "Global Warming: It's All About Carbon."  Who knew that a carbon atom could have such a charming persona?  Albeit sobering in the context of too much atmospheric carbon - released through decades of use of fossil fuels - creating the greenhouse effect encircling the globe.

A keyword search in OBIS on carbon and climate yields over 1000 titles; possibly none of them are as pithy and helpful for someone new to the topic as Krulwich's videos created with Odd Todd.  Do come back to the library for in-depth understanding of climate disruption: search climatic changes or climate change mitigation for best results.  Climate change: a very short introduction is an excellent first choice, or, for a fuller review of carbon, check out Carbon age : how life's core element has become civilization's greatest threat.

Wednesday, September 21, 2016

DNA + Light: Talk by Carlos E. Crespo-Hernández

Talk sponsored by the Department of Chemistry and Biochemistry 
Thursday, September 22, 2016
4:45pm  Science Center A255

DNA + Light: From Nucleic Acid Bases to Modifications that Enable Damage to Carcinoma Cells

Carlos E. Crespo-Hernández, Department of Chemistry and Center for Chemical Dynamics, Case Western Reserve University, Cleveland, OH, United States.

Partial abstract: Photodynamic therapy (PDT) is an effective treatment option for a variety of skin cancers and diseases. Recently, the DNA analog 4‑thiothymidine (4tT) has demonstrated efficacy as a PDT agent against rapidly-dividing malignant cells while leaving normal cells unharmed. Its phototoxic activity and low off-target effects make this thiobase a highly promising PDT candidate. However, the depth of tissues able to be treated with 4tT is limited by its absorption cutoff at ~365 nm. A thiobase photosensitizer able to absorb longer wavelengths of light is needed because longer wavelengths are able to reach more invasive skin cancers and diseases. Recently, we found that doubling the sulfur substitution of the nucleobase increases its photoreactivity and simultaneously shifts its absorption spectrum into the near-visible region (~395 nm) where light can penetrate more than 100% deeper into tissues. In vitro screening experiments performed in our laboratory using epidermoid carcinoma cells (A431) have revealed several doubly-substituted thiobase derivatives that are effective photosensitizes.

Several relevant books are accessible electronically through OBIS:
Find them all and many other related titles with a keyword search on photodynamic therapy

Friday, September 16, 2016

Metal-Organic Frameworks as Biocompatible Platforms: publication by S. A. FitzGerald, et al.

New publication from a collaboration involving Stephen A. FitzGerald, Professor of Physics and eleven other authors from organizations in California, Illinois, Texas, and France.

Levine, Dana J., Tomce Runcevski, Matthew T. Kapelewski, Benjamin K. Keitz, Julia Oktawiec, Douglas A. Reed, Jarad A. Mason, Henry Jiang, Kristen A. Colwell, Christina M. Legendre, Stephen A. FitzGerald, Jeffrey R. Long. 2016.

"Olsalaiine-Based Metal-Organic Frameworks as Biocompatible Platforms for H2 Adsorption and Drug Delivery." Journal of the American Chemical Society 138 (32): 10143-10150.

From the Abstract:  “The low toxicity, high surface areas, and coordinatively unsaturated metal sites make these M-2(olz) materials promising for a range of potential applications, including drug delivery in the treatment of gastrointestinal diseases.”

View online at ACS; subscriber access by Oberlin College Library and OhioLINK

Monday, August 29, 2016

Here we go! Welcome to the fall semester

8:15am and the Perlik Commons of Oberlin College Science Center is humming!  Welcome to all, students and staff -- so happy to see the coffee cart in operation for the school year.  The science library is humming, too, somewhat more quietly. ;-)  Sign up for a study carrel and grab your spot for the semester.

Thursday, August 25, 2016

Love your park. NPS turns 100 today!

The National Park Service has been celebrating its centennial all year - today is the day of the NPS founding, August 25, 1916.  Thank you to the NPS founders: Theodore Roosevelt, Horace M. Albright, Stephen Mather, and Woodrow Wilson.  NPS is offering free admission to any of its 412 parks this weekend - so get out there!  The beginning of a new semester isn't the best timing for a park visit, of course.  Enjoy them virtually with Ken Burns The National Parks : America's Best Idea (a Kanopy streaming video).

Friday, August 05, 2016

Citizen Science Projects Celebrate National Park Service Centennial

Five National Park Citizen Science Projects Anyone Can Join: Celebrate the NPS centennial by lending a hand. -- Sierra Club

It's unlikely that anyone on campus will be participating in NPS citizen science projects on the actual centennial date, August 25 - we will be in the midst of new student orientation that day.  But the opportunities for citizen science projects throughout the year are numerous and varied.  Check it out!

Citizen science projects are ongoing worldwide, investigating many different subjects under a whole host of sponsors; see Discover magazine's Top Ten citizen science projects of 2015 for a hint at the diversity of options.  Find more at SciStarter.

Back to the National Park Service centennial - you can visit a lovely National Park within a one hour drive of Oberlin.  It doesn't have the awesome peaks of Glacier or the wildlife of Yellowstone or wild ocean shores of Acadia, but it offers excellent hiking trails and hundreds of acres of beautiful Ohio forest, fields, meadows, wetlands and streams.  Plus the old Ohio-Erie canal towpath for biking and Blossom Music Center, summer home of the Cleveland Orchestra.  Visit the Cuyahoga Valley National Park in every season to appreciate all there it has.