Thursday, January 03, 2019

New publications by FitzGerald and Howard

 Stephen A. FitzGerald, Professor of Physics
publisher's site
Kapelewski, M. T., T. Runcevski, J. D. Tarver, H. Z. H. Jiang, K. E. Hurst, P. A. Parilla, A. Ayala, T. Gennett, S. A. FitzGerald, C. M. Brown, and J. R. Long. 2018. Record High Hydrogen Storage Capacity in the Metal-Organic Framework Ni-2(m-dobdc) at Near-Ambient Temperatures. Chemistry of Materials 30:8179-8189.
Access from OhioLINK Electronic Journal Center

Christopher D. Howard, Assistant Professor of Neuroscience
publisher's site
Schuweiler, D. R., C. D. Howard, E. S. Ramsson, and P. A. Garris. 2018. Improving in Situ Electrode Calibration with Principal Component Regression for Fast-Scan Cyclic Voltammetry. Analytical Chemistry 90:13434-13442.

Access from OhioLINK Electronic Journal Center

Thursday, December 20, 2018

Faculty publish in Astrophysical Journal and Physics of the Dark Universe

Recent publications co-authored by faculty in Physics and Astronomy:

Scudder, Jillian M.
Pan H, Lin L, Hsieh B, Xiao T, Gao Y, Ellison SL, Scudder JM, Barrera-Ballesteros J, Yuan F, Saintonge A, Wilsons CD, Hwang HS, De Looze I, Gao Y, Ho LC, Brinks E, Mok A, Brown T, Davis TA, Williams TG, Chung A, Parsons H, Bureau M, Sargent MT, Chung EJ, Kim E, Liu T, Michalowski MJ, Tosaki T.
The effect of galaxy interactions on molecular gas properties. Astrophysical Journal 2018 DEC 1;868(2):132.
Stalnaker, Jason E.
Afach S, Budker D, DeCamp G, Dumont V, Grujic ZD, Guo H, Kimball DFJ, Kornack TW, Lebedev V, Li W, Masia-Roig H, Nix S, Padniuk M, Palm CA, Pankow C, Penaflor A, Peng X, Pustelny S, Scholtes T, Smiga JA, Stalnaker JE, Weis A, Wickenbrock A, Wurm D.
Characterization of the global network of optical magnetometers to search for exotic physics (GNOME). Physics of the Dark Universe 2018 DEC;22:162-80.

Stinebring, Daniel R.
Brook PR, Karastergiou A, McLaughlin MA, Lam MT, Arzoumanian Z, Chatterjee S, Cordes JM, Crowter K, DeCesar M, Demorest PB, Dolch T, Ellis JA, Ferdman RD, Ferrara E, Fonseca E, Gentile PA, Jones G, Jones ML, Lazio TJW, Levin L, Lorimer DR, Lynch RS, Ng C, Nice DJ, Pennucci TT, Ransom SM, Ray PS, Spiewak R, Stairs IH, Stinebring DR, Stovall K, Swiggum JK, Zhu WW. 
The NANOGrav 11-year data set: Pulse profile variability. Astrophysical Journal  2018 DEC 1;868(2):122.

Friday, November 23, 2018

Thompson, Katz and Sheehan: Chemical comparison of Prunus africana bark and pygeum products marketed for prostate health.

New publication from Rob Thompson, Professor of Chemistry, with senior Daniel Katz and Brendan Sheehan (OC'18, biochemistry).

Chemical comparison of Prunus africana bark and pygeum products marketed for prostate health.
Journal of Pharmaceutical and Biomedical Analysis Vol. 163, 30 January 2019, pp. 162-169

Access this title at the OhioLINK Electronic Journal Center or at the publisher's site, Elsevier's ScienceDirect.

From the introduction and conclusions:
"Pygeum is the powdered bark of Prunus africana (also called Pygeum africanum), an evergreen tree that grows across the mountainous regions of Africa. Both the powder and a lipophilic extract are sold commercially under the same name... Ingestion of pygeum has been found to inactivate the androgen receptor and inhibit prostate cancer cell growth."
[Conclusions after chemical analysis of samples of both bark and pygeum powder:]
Harvesting Prunus africana bark. 
Credit: SouthWorld, May 1, 2016
"The amounts per gram of the BPH-active compounds atranorin, atraric acid, total ferulic acid, and total beta-sitosterol and the fractions of free beta-sitosterol were quite different in bark from Prunus africana and in the contents of commercial pygeum capsules, contents purported to be derivatives of the same bark. This was unexpected and suggested that the BPH-active components in commercial pygeum may not be fully sourced from natural materials as labeled. Also unexpected was that no N-butylbenzene sulfonamide was found in any sample. The variation in the composition of four bark samples, two of which were botanical reference materials, demonstrated the need for a phytochemical standard for pygeum, with reference values for the BPH-active compounds studied here."

Tuesday, September 18, 2018

What Neil deGrasse Tyson Thinks Higher Ed Gets Wrong

In this interview with The Chronicle of Higher Education, Tyson discusses "how to explain science to the masses and [rips] into what he sees as higher education’s misguided incentive system, valuing research over teaching and public service and not creating space for people like him to flourish. 'It’s a sad fact,' he says, 'for the future of science in America.' "

Astrophysics for People in a Hurry is one of Tyson's most recent books.  The science library's copy is checked out, but there are plenty of other copies to borrow through OhioLINK.

Wednesday, August 08, 2018

Jordan Price and students publish in Journal of Bacteriology

New publication by Jordan Price, Assistant Professor of Biology, with students Kallie Jiang and Abby Galantowicz, and collaborators at Univ Calif Berkeley:

Price, Jordan V.; Jiang, Kallie; Galantowicz, Abby; Freifeld, A., & Vance, R. E. (2018). Legionella pneumophila is directly sensitive to 2-deoxyglucose-phosphate via its UhpC transporter but is indifferent to shifts in host cell glycolytic metabolism. Journal of Bacteriology, 200(16), 176. doi:10.1128/JB.00176-18 ER
Importance of this research:  "We explored the relationship between macrophage glycolysis and replication of an intracellular bacterial pathogen, Legionella pneumophila. Previous studies demonstrated that a glycolysis inhibitor, 2-deoxyglucose (2DG), blocks replication of L. pneumophila during infection of macrophages, leading to speculation that L. pneumophila may exploit macrophage glycolysis. We isolated L. pneumophila mutants resistant to the inhibitory effect of 2DG in macrophages, identifying a L. pneumophila hexose-phosphate transporter, UhpC, that is required for bacterial sensitivity to 2DG during infection. Our results reveal how a bacterial transporter mediates the direct antimicrobial effect of a toxic metabolite. Moreover, our results indicate that neither induction nor impairment of host glycolysis inhibits intracellular replication of L. pneumophila, which is consistent with a view of L. pneumophila as a metabolic generalist."

Monday, August 06, 2018

New publications by Stinebring (Physics & Astronomy) and Moore (Biology)

Recent publications by Dan Stinebring, Francis D Federighi Professor of Physics; and Mike Moore, Professor of Biology:

Lam, M. T., Ellis, J. A., Grillo, G., Jones, M. L., Hazboun, … Daniel R. Stinebring, et al. (2018). A second chromatic timing event of interstellar origin toward PSR J1713+0747. Astrophysical Journal, 861(2), 132. 10.3847/1538-4357/aac770 ER

an Open Access journal
from Taylor & Francis
Zhu, Z., Wang, J., Cai, Y., Zhao, K., Michael J. Moore, & Wang, H. (2018). Complete plastome sequence of erythropalum scandens (erythropalaceae), an edible and medicinally important liana in china. Mitochondrial Dna Part B-Resources, 3(1), 139-140. 10.1080/23802359.2017.1413435 ER

Thursday, July 05, 2018

Angie Roles publishes in Ecology and Evolution

Blandy Experimental Farm, Boyce, Virginia
Recent research by Associate Professor of Biology Angie Roles and collaborators "assessed phenotypes associated with survival and reproductive success in over 30,000 plants representing 100 mutation accumulation lines of Arabidopsis thaliana across four temporal environments at a single field site." The authors conclude, "The combination of large environmental variance with a mean effect of mutation near zero suggests that mutations could contribute substantially to standing genetic variation."

Rutter, Matthew T., Roles, Angela J., & Fenster, Charles B. (2018). Quantifying natural seasonal variation in mutation parameters with mutation accumulation lines. Ecology and Evolution, 8(11), 5575-5585. 10.1002/ece3.4085  (Open Access)