Wednesday, January 12, 2022

Shuming Chen, Assistant Professor of Chemistry and Biochemistry, publishes in Angewandte Chemie-International Edition

Huffman, B. J., Chu, T., Hanaki, Y., Wong, J. J., Chen, Shuming M., Houk, K. N., & Shenvi, R. 2022. A.Stereodivergent Attached-Ring Synthesis via Non-Covalent Interactions: A Short Formal Synthesis of Merrilactone A. Angewandte Chemie-International Edition.  61 10.1002/anie.202114514  First published 24 Nov. 2021.


From the conclusion: "Here we disclose a surprising and, to the best of our knowledge, unprecedented model for divergent attached-ring stereocontrol via base- versus Lewis acid-mediated γ-selective butenolide Michael addition." 


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